(2023)
COVID-19 infection and ginseng: Predictive influenza virus strains and non-predictive COVID-19 vaccine strains.
JOURNAL OF GINSENG RESEARCH.
47,
2
(2023)
Immunization with a Pneumococcal pep27 Mutant Strain Alleviates Atopic Dermatitis through the Upregulation of Regulatory T-Cell Activity and Epithelial Barrier Function and Suppressing TSLP Expression.
JOURNAL OF INVESTIGATIVE DERMATOLOGY.
143,
1
(2022)
Pep27 Mutant Immunization Inhibits Caspase-14 Expression to Alleviate Inflammatory Bowel Disease via Treg Upregulation.
MICROORGANISMS.
10,
9
(2022)
Pneumococcal pep27-mutant inhibits Wnt5a expression via the regulation
of T helper cells to attenuate colitis.
INTERNATIONAL IMMUNOPHARMACOLOGY.
109,
8
(2021)
Corona-Cov-2 (COVID-19) and ginseng: Comparison of possible use in COVID-19 and influenza.
JOURNAL OF GINSENG RESEARCH.
45,
4
(2021)
Crystal Structure of the Pneumococcal Vancomycin-Resistance Response Regulator DNA-Binding Domain.
MOLECULES AND CELLS.
44,
3
(2020)
ClpL is a functionally active tetradecameric AAA plus chaperone, distinct from hexameric/dodecameric ones.
FASEB JOURNAL.
34,
11
(2020)
Korean red ginseng alleviates neuroinflammation and promotes cell survival in intermittent heat stress-induced rat brain by suppressing oxidative stress via eastrogen receptor beta and brain derived neurotrophic factor upregulation..
JOURNAL OF GINSENG RESEARCH.
44,
4
(2020)
Ginseng alleviates microbial infections of the respiratory tract: a review..
JOURNAL OF GINSENG RESEARCH.
44,
2
(2019)
Pneumococcal pep27 mutant immunization suppresses allergic asthma in mice..
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS.
514,
1
(2019)
Korean Red Ginseng enhances pneumococcal Δpep27 vaccine efficacy by inhibiting reactive oxygen species production.
JOURNAL OF GINSENG RESEARCH.
43,
2
(2019)
Immunization with attenuated non-transformable pneumococcal pep27 and comD mutant provides serotype-independent protection against pneumococcal infection..
VACCINE.
37,
1
(2018)
Estrogen receptor-β of microglia underlies sexual differentiation of neuronal protection via ginsenosides in mice brain.
CNS NEUROSCIENCE & THERAPEUTICS.
24,
10
(2018)
Induction of the pneumococcal vncRS operon by lactoferrin is essential for pneumonia.
VIRULENCE.
9,
1
(2018)
Allicin induces beige-like adipocytes via KLF15 signal cascade..
JOURNAL OF NUTRITIONAL BIOCHEMISTRY.
64,
1
(2018)
Adenylate kinase potentiates the capsular polysaccharide by modulating Cps2D in Streptococcus pneumoniae D39.
EXPERIMENTAL AND MOLECULAR MEDICINE.
50,
(2018)
ATF3 Stimulates IL-17A by Regulating Intracellular Ca2+/ROS-Dependent IL-1 beta Activation During Streptococcus pneumoniae Infection.
FRONTIERS IN IMMUNOLOGY.
9,
(2018)
Effect of Korean Red Ginseng extracts on drug-drug interactions.
JOURNAL OF GINSENG RESEARCH.
42,
3
(2018)
Effective prevention of secondary pneumococcal infection following influenza virus infection.
FUTURE MICROBIOLOGY.
13,
9
단행본
(2007)
약품미생물학연습.
신일북스.
공동
(2006)
신종합미생물학.
신일상사.
공동
(2005)
미생물학 연습.
신일상사.
공동
(2005)
종합미생물학.
신일상사.
공동
(2001)
실험미생물학.
신일상사.
공동
(1999)
신약품미생물학.
공동
특허/프로그램
Vaccine Comprising Recombinant ClpP Protein of Streptococcus pneumoniae.
12/953,677.
20140909.
미국
ｐｅｐ27 유전자 돌연변이를 포함하는 약독화된 폐렴구균 균주 및 이의 용도(Attenuated Streptococcus pneumococcus comprising mutated pep27 gene and use the same).
10-1252911-0000.
20130403.
대한민국
재조합 폐렴구균 ClpP 단백질을 포함하는 백신.
2005-512815.
20101105.
일본
VACCINE COMPOSITION FOR PREVENTION OR TREATMENT OF PNEUMOCOCCAL INFECTIONS COMPRISING VNCR／S OPERON-DISABLED STREPTOCOCCUS PNEUMONIA MUTANT STRAIN OR PEP27 PEPTIDE..
PCT/KR2009/004428.
20100401.
PCT
재조합 폐렴구균 ClpP 단백질을 포함하는 백신..
10-0814616.
20080311.
대한민국
Vaccine comprising recombinant ClpP protein of Streptococcus pneumoniae..
2003288788.
20070215.
오스트레일리아
수상/공훈
농림축산식품부 장관상 (2015.12.31)
의산 최우수논문상 (고려인삼학회 2013. 4. 16)
녹암학술상 (대한약학회 2009. 10. 15)
학술회의논문
(2016)
Protective effect of Korean red ginseng from pneumonia/sepsis and meningitis..
식품영양학회 추계 초록집.
대한민국
(2016)
Korean red ginseng as an anti-stress immune-potentiator via ER-β modulation..
8th Annual Pharma Middle East Congress.
아랍에미리트
(2016)
Pneumococcal pep27 mutant immunization stimulates cytokine secretion and confers long-term immunity with a wide range of protection, including against non-typeable strains..
16th International Congress of Immunology.
오스트레일리아
(2016)
Modulation of immune system by Korean red ginseng via potentiation of cell survival and inhibition of inflammation in pneumococcal infection..
16th International Congress of Immunology.
오스트레일리아
(2016)
Screening, characterization and engineering of a single-chain antibody variable fragment (Scfv) against PspA from Streptococcus pneumoniae..
ISPPD10.
영국
(2016)
ClpL N-terminal domain is involved in chaperone activity and middle domain in oligomer stabilizer..
ISPPD10.
영국
(2016)
Streptococcus pneumoniae ilvC mediates virulence via Ply and LytA upregulation..
ISPPD10.
영국
(2015)
Korean Red Ginseng prevents pneumococcal sepsis in vivo by potentiating cell survival and diminishing inflammation..
고려인삼학회 추계학술대회.
대한민국
(2015)
Protection of neuron cells from apoptosis by Korean red ginseng via ERβ/PI3K signalling..
Pharma Middle East.
아랍에미리트
(2015)
Inhibition of autolysis by lipase LipA in Streptococcus pneumoniae sepsis..
대한약학회 추계학술대회.
대한민국
(2015)
M-domain independent chaperone activity of ClpL..
한국미생물학회 국제학술대회.
대한민국
(2015)
Adenylate kinase modulates pneumococcal capsule via autophosphotyrosine kinase..
2015 한국미생물학회 국제학술대회.
대한민국
(2015)
Modulation of Streptococcus pneumoniae virulence by ilvC..
2015 한국미생물학회 국제학술대회.
대한민국
(2014)
Differential Modulation of Cytokine Production in Gram-negative and Gram-positive Bacterial Infection by ATF3, a Stress Inducible Eukaryotic Gene..
한국미생물연합 국제학술대회.
대한민국
(2014)
Streptococcus pneumoniae ClpL inhibits adherence to A549 human lung cells through Rap1-mediated actin remodelling..
9th ISPPD.
인도
(2014)
Adenylate kinase required for pneumococcal growth and capsular synthesis.
9th ISPPD.
인도
(2014)
Macrophages play a key role in the protection by Streptococcus pneumoniae pep27 mutant vaccine.
9th ISPPD.
인도
(2014)
Streptococcus pneumoniae pep27 mutant is avirulent and its immunization provides broad and long-lasting protection..
9th ISPPD.
인도
(2014)
ATF3 provides resistance to Streptococcus pneumoniae infection via cytokine upregulation..
9th ISPPD.
인도
(2014)
Pneumococcal ClpL is a Mn-dependent chaperone without auxiliary factors..
9th ISPPD.
인도
